منابع مشابه
Mitomycins syntheses: a recent update
Mitomycins are a class of very potent antibacterial and anti-cancer compounds having a broad activity against a range of tumours. They have been used in clinics since the 1960's, and the challenges represented by their total synthesis have challenged generations of chemists. Despite these chemical and medicinal features, these compounds, in racemic form, have succumbed to total synthesis only f...
متن کاملRecent advances in chemoenzymatic peptide syntheses.
Chemoenzymatic peptide synthesis is the hydrolase-catalyzed stereoselective formation of peptide bonds. It is a clean and mild procedure, unlike conventional chemical synthesis, which involves complicated and laborious protection-deprotection procedures and harsh reaction conditions. The chemoenzymatic approach has been utilized for several decades because determining the optimal conditions for...
متن کاملRecent developments in preparative enzymatic syntheses of carbohydrates.
Andrew Rowan graduated from Queen’s University Belfast (2004) with a degree in medicinal chemistry. During this time, he has spent two summer placements as a synthetic chemist in the chemical industry at C.S.S. (Chemical Synthesis Services). He is currently studying for his PhD under the supervision of Chris Hamilton at Queen’s University Belfast. His research focuses on the synthesis of cell-p...
متن کاملNITROIMIDAZOLES XI [I]. SYNTHESES OF DISUBSTITUTED NITROIMIDAZOLYLQUINOLINES
Reaction of substituted-aniline (8) with ethyl (l-methyl-5-nitroimidazole-2- carbonyl) acetate (9) gave 4-hydroxy-2-(l-methyl-5-nitro-2-imidazolyl)- substituted-quinolines (lo), which were converted to compound 11 with phosphorus oxychloride. Substituted-2-(l-methyl-5-nitro-2-imidazo1yl)-4.- methyl-(or phenyl-) quinolines (14) were prepared through the reaction of 2- acetyl-5-nitro-1-methy...
متن کاملRecent Progress on Enyne Metathesis: Its Application to Syntheses of Natural Products and Related Compounds
Abstract: Olefin metathesis using ruthenium carbene complexes is a useful method in synthetic organic chemistry. Enyne metathesis is also catalyzed by these complexes and various carboand heterocycles could be synthesized from the corresponding enynes. Dienyne metathesis, cross enyne metathesis and ring-opening enyne metathesis have been further developed. Various complicated compounds, such as...
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ژورنال
عنوان ژورنال: HETEROCYCLES
سال: 2013
ISSN: 0385-5414
DOI: 10.3987/rev-13-782